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Cobalt in PDB 1igx: Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.
Enzymatic activity of Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.
All present enzymatic activity of Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.:
1.14.99.1;
1.14.99.1;
Protein crystallography data
The structure of Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1., PDB code: 1igx
was solved by
M.G.Malkowski,
E.D.Thuresson,
W.L.Smith,
R.M.Garavito,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 20.00 / 3.10 |
| Space group | P 65 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 182.170, 182.170, 103.110, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 22.8 / 29.4 |
Cobalt Binding Sites:
The binding sites of Cobalt atom in the Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.
(pdb code 1igx). This binding sites where shown within
5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1., PDB code: 1igx:
In total only one binding site of Cobalt was determined in the Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1., PDB code: 1igx:
Cobalt binding site 1 out of 1 in 1igx
Go back to
Cobalt Binding Sites List in 1igx
Cobalt binding site 1 out
of 1 in the Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 1 of Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1. within 5.0Å range:
|
Reference:
M.G.Malkowski,
E.D.Thuresson,
K.M.Lakkides,
C.J.Rieke,
R.Micielli,
W.L.Smith,
R.M.Garavito.
Structure of Eicosapentaenoic and Linoleic Acids in the Cyclooxygenase Site of Prostaglandin Endoperoxide H Synthase-1. J.Biol.Chem. V. 276 37547 2001.
ISSN: ISSN 0021-9258
PubMed: 11477109
DOI: 10.1074/JBC.M105982200
Page generated: Sun Jul 13 17:35:26 2025
ISSN: ISSN 0021-9258
PubMed: 11477109
DOI: 10.1074/JBC.M105982200
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