Cobalt in PDB 1zzb: Crystal Structure of Coii Hppe in Complex with Substrate

The structure of Crystal Structure of Coii Hppe in Complex with Substrate, PDB code: 1zzb was solved by L.J.Higgins, F.Yan, P.Liu, H.W.Liu, C.L.Drennan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.12 / 2.30
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	86.240, 86.240, 220.150, 90.00, 90.00, 120.00
R / Rfree (%)	23.8 / 28.1

The binding sites of Cobalt atom in the Crystal Structure of Coii Hppe in Complex with Substrate (pdb code 1zzb). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Crystal Structure of Coii Hppe in Complex with Substrate, PDB code: 1zzb:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Crystal Structure of Coii Hppe in Complex with Substrate


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of Coii Hppe in Complex with Substrate within 5.0Å range: probe atom residue distance (Å) B Occ A:Co199 b:45.6 occ:1.00 O14 A:S0H1002 1.9 62.4 1.0 OE2 A:GLU142 2.1 44.0 1.0 NE2 A:HIS138 2.1 54.2 1.0 NE2 A:HIS180 2.3 50.4 1.0 O A:HOH1035 2.5 44.5 1.0 CD A:GLU142 3.0 45.5 1.0 CD2 A:HIS138 3.1 53.8 1.0 CE1 A:HIS180 3.1 48.7 1.0 CE1 A:HIS138 3.1 53.3 1.0 OE1 A:GLU142 3.3 47.2 1.0 CD2 A:HIS180 3.3 48.2 1.0 P1 A:S0H1002 3.4 62.9 1.0 O15 A:S0H1002 3.8 62.9 1.0 ND2 A:ASN135 4.0 59.6 1.0 O13 A:S0H1002 4.2 62.4 1.0 OD1 A:ASN197 4.2 51.1 1.0 ND1 A:HIS138 4.2 54.4 1.0 CG A:HIS138 4.2 56.0 1.0 ND1 A:HIS180 4.3 48.7 1.0 CG A:HIS180 4.4 48.7 1.0 CG A:GLU142 4.4 42.4 1.0 C2 A:S0H1002 4.5 63.5 1.0 CB A:GLU142 4.8 38.4 1.0

Cobalt binding site 2 out of 2 in the Crystal Structure of Coii Hppe in Complex with Substrate


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Crystal Structure of Coii Hppe in Complex with Substrate within 5.0Å range: probe atom residue distance (Å) B Occ B:Co199 b:41.1 occ:1.00 NE2 B:HIS138 2.0 50.1 1.0 O15 B:S0H1001 2.1 50.9 1.0 O6 B:S0H1001 2.1 46.2 1.0 NE2 B:HIS180 2.1 39.7 1.0 OE1 B:GLU142 2.2 40.5 1.0 CD2 B:HIS138 3.0 50.4 1.0 CE1 B:HIS180 3.0 41.5 1.0 CE1 B:HIS138 3.1 48.1 1.0 CD2 B:HIS180 3.1 40.9 1.0 CD B:GLU142 3.1 43.8 1.0 P1 B:S0H1001 3.2 49.2 1.0 C3 B:S0H1001 3.3 48.7 1.0 O14 B:S0H1001 3.3 48.0 1.0 OE2 B:GLU142 3.4 45.9 1.0 C2 B:S0H1001 3.7 48.6 1.0 C1 B:S0H1001 4.1 48.7 1.0 CG B:HIS138 4.1 50.7 1.0 ND1 B:HIS138 4.1 50.0 1.0 ND1 B:HIS180 4.2 39.7 1.0 CG B:HIS180 4.3 39.5 1.0 OD1 B:ASN197 4.4 46.6 1.0 O13 B:S0H1001 4.5 48.8 1.0 CG B:GLU142 4.5 41.1 1.0 OD1 B:ASN135 4.7 67.5 1.0 CB B:GLU142 4.8 39.9 1.0 O B:HOH1011 4.9 41.7 1.0

L.J.Higgins, F.Yan, P.Liu, H.W.Liu, C.L.Drennan. Structural Insight Into Antibiotic Fosfomycin Biosynthesis By A Mononuclear Iron Enzyme Nature V. 437 838 2005.
ISSN: ISSN 0028-0836
PubMed: 16015285
DOI: 10.1038/NATURE03924