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Cobalt in PDB 4xyj: Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275
Enzymatic activity of Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275
All present enzymatic activity of Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275:
2.7.1.11;
2.7.1.11;
Protein crystallography data
The structure of Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275, PDB code: 4xyj
was solved by
F.Forouhar,
B.A.Webb,
F.-E.Szu,
J.Seetharaman,
D.L.Barber,
L.Tong,
Northeast Structural Genomics Consortium (Nesg),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 49.69 / 3.10 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 137.199, 159.329, 170.533, 90.00, 104.20, 90.00 |
| R / Rfree (%) | 22.1 / 24.6 |
Other elements in 4xyj:
The structure of Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275 also contains other interesting chemical elements:
| Magnesium | (Mg) | 15 atoms |
Cobalt Binding Sites:
The binding sites of Cobalt atom in the Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275
(pdb code 4xyj). This binding sites where shown within
5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275, PDB code: 4xyj:
Jump to Cobalt binding site number: 1; 2;
In total 2 binding sites of Cobalt where determined in the Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275, PDB code: 4xyj:
Jump to Cobalt binding site number: 1; 2;
Cobalt binding site 1 out of 2 in 4xyj
Go back to
Cobalt Binding Sites List in 4xyj
Cobalt binding site 1 out
of 2 in the Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 1 of Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275 within 5.0Å range:
|
Cobalt binding site 2 out of 2 in 4xyj
Go back to
Cobalt Binding Sites List in 4xyj
Cobalt binding site 2 out
of 2 in the Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 2 of Crystal Structure of Human Phosphofructokinase-1 in Complex with Atp and Mg, Northeast Structural Genomics Consortium Target HR9275 within 5.0Å range:
|
Reference:
B.A.Webb,
F.Forouhar,
F.-E.Szu,
J.Seetharaman,
L.Tong,
D.L.Barber.
Structures of Human Phosphofructokinase-1 and Atomic Basis of Cancer-Associated Mutations To Be Published.
Page generated: Sun Jul 13 20:11:47 2025
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