Cobalt in PDB 7f7l: Crystal Structure of AKR4C17 Bound with Nadph

The structure of Crystal Structure of AKR4C17 Bound with Nadph, PDB code: 7f7l was solved by H.Li, Y.Yang, Y.Hu, C.-C.Chen, J.-W.Huang, J.Min, L.Dai, R.-T.Guo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.82 / 2.25
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	77.426, 77.426, 452.752, 90, 90, 120
R / Rfree (%)	18.1 / 22.6

The binding sites of Cobalt atom in the Crystal Structure of AKR4C17 Bound with Nadph (pdb code 7f7l). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Crystal Structure of AKR4C17 Bound with Nadph, PDB code: 7f7l:

Cobalt binding site 1 out of 1 in the Crystal Structure of AKR4C17 Bound with Nadph


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of AKR4C17 Bound with Nadph within 5.0Å range: probe atom residue distance (Å) B Occ A:Co401 b:15.7 occ:0.80 O A:HOH510 1.8 23.4 1.0 NE2 A:HIS171 1.9 19.6 1.0 CE1 A:HIS171 2.8 25.9 1.0 CD2 A:HIS171 3.1 18.6 1.0 ND1 A:HIS171 4.0 23.6 1.0 CG A:HIS171 4.1 23.3 1.0 O A:ALA168 4.1 17.1 1.0 O A:LEU165 4.5 19.9 1.0 O A:HOH513 4.5 37.5 1.0 O A:ARG169 4.7 22.0 1.0

H.Li, Y.Yang, Y.Hu, C.C.Chen, J.W.Huang, J.Min, L.Dai, R.T.Guo. Structural Analysis and Engineering of Aldo-Keto Reductase From Glyphosate-Resistant Echinochloa Colona J Hazard Mater V. 436 29191 2022.
ISSN: ESSN 1873-3336
DOI: 10.1016/J.JHAZMAT.2022.129191