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Cobalt in PDB 8sse: Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8
Enzymatic activity of Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8
All present enzymatic activity of Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8:
2.1.1.13;
2.1.1.13;
Protein crystallography data
The structure of Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8, PDB code: 8sse
was solved by
K.Yamada,
J.Mendoza,
M.Koutmos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 49.30 / 3.15 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 166.135, 95.844, 238.745, 90, 91.96, 90 |
| R / Rfree (%) | 24.5 / 30.7 |
Cobalt Binding Sites:
The binding sites of Cobalt atom in the Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8
(pdb code 8sse). This binding sites where shown within
5.0 Angstroms radius around Cobalt atom.
In total 6 binding sites of Cobalt where determined in the Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8, PDB code: 8sse:
Jump to Cobalt binding site number: 1; 2; 3; 4; 5; 6;
In total 6 binding sites of Cobalt where determined in the Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8, PDB code: 8sse:
Jump to Cobalt binding site number: 1; 2; 3; 4; 5; 6;
Cobalt binding site 1 out of 6 in 8sse
Go back to
Cobalt Binding Sites List in 8sse
Cobalt binding site 1 out
of 6 in the Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 1 of Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8 within 5.0Å range:
|
Cobalt binding site 2 out of 6 in 8sse
Go back to
Cobalt Binding Sites List in 8sse
Cobalt binding site 2 out
of 6 in the Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 2 of Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8 within 5.0Å range:
|
Cobalt binding site 3 out of 6 in 8sse
Go back to
Cobalt Binding Sites List in 8sse
Cobalt binding site 3 out
of 6 in the Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 3 of Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8 within 5.0Å range:
|
Cobalt binding site 4 out of 6 in 8sse
Go back to
Cobalt Binding Sites List in 8sse
Cobalt binding site 4 out
of 6 in the Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 4 of Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8 within 5.0Å range:
|
Cobalt binding site 5 out of 6 in 8sse
Go back to
Cobalt Binding Sites List in 8sse
Cobalt binding site 5 out
of 6 in the Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 5 of Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8 within 5.0Å range:
|
Cobalt binding site 6 out of 6 in 8sse
Go back to
Cobalt Binding Sites List in 8sse
Cobalt binding site 6 out
of 6 in the Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 6 of Methionine Synthase, C-Terminal Fragment, Cobalamin and Reactivation Domains From Thermus Thermophilus HB8 within 5.0Å range:
|
Reference:
J.Mendoza,
M.Purchal,
K.Yamada,
M.Koutmos.
Structure of Full-Length Cobalamin-Dependent Methionine Synthase and Cofactor Loading Captured in Crystallo Biorxiv 2023.
ISSN: ISSN 2692-8205
DOI: 10.1101/2023.06.15.544998
Page generated: Sun Jul 13 22:05:21 2025
ISSN: ISSN 2692-8205
DOI: 10.1101/2023.06.15.544998
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