Cobalt in PDB 9ciy: Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter

The structure of Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter, PDB code: 9ciy was solved by E.R.Xing, L.A.Yatsunyk, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.20 / 2.40
Space group	P 42 2 2
Cell size a, b, c (Å), α, β, γ (°)	71.849, 71.849, 41.637, 90, 90, 90
R / Rfree (%)	19.7 / 23.2

The structure of Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter also contains other interesting chemical elements:

Potassium

(K)

4 atoms

The binding sites of Cobalt atom in the Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter (pdb code 9ciy). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 3 binding sites of Cobalt where determined in the Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter, PDB code: 9ciy:
Jump to Cobalt binding site number: 1; 2; 3;

Cobalt binding site 1 out of 3 in the Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter within 5.0Å range: probe atom residue distance (Å) B Occ A:Co105 b:127.2 occ:0.25 CO A:NCO105 0.0 127.2 0.2 N6 A:NCO105 2.0 119.8 0.2 N4 A:NCO105 2.0 119.8 0.2 N5 A:NCO105 2.0 124.2 0.2 N3 A:NCO105 2.0 124.2 0.2 N2 A:NCO105 2.0 122.5 0.2 N1 A:NCO105 2.0 122.5 0.2 OP1 A:DG21 4.8 109.6 1.0 OP2 A:DG22 4.8 86.2 1.0

Cobalt binding site 2 out of 3 in the Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter within 5.0Å range: probe atom residue distance (Å) B Occ A:Co106 b:122.0 occ:1.00 CO A:NCO106 0.0 122.0 1.0 N2 A:NCO106 2.0 115.5 1.0 N5 A:NCO106 2.0 83.0 1.0 N6 A:NCO106 2.0 109.0 1.0 N4 A:NCO106 2.0 107.1 1.0 N3 A:NCO106 2.0 94.9 1.0 N1 A:NCO106 2.0 106.1 1.0 O A:HOH201 3.5 103.4 1.0 O4 A:DT25 4.2 105.0 1.0 O4 A:DT13 4.3 105.9 1.0

Cobalt binding site 3 out of 3 in the Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 3 of Right-Left Hybrid Parallel G-Quadruplex From NSD1 Promoter within 5.0Å range: probe atom residue distance (Å) B Occ A:Co107 b:109.3 occ:0.61 CO A:NCO107 0.0 109.3 0.6 N6 A:NCO107 2.0 85.5 0.6 N1 A:NCO107 2.0 98.2 0.6 N4 A:NCO107 2.0 92.8 0.6 N2 A:NCO107 2.0 78.7 0.6 N3 A:NCO107 2.0 78.6 0.6 N5 A:NCO107 2.0 93.8 0.6 OP2 A:DG26 4.0 72.4 1.0 O3' A:DG26 4.7 97.5 1.0 C4 A:DT14 4.8 94.5 1.0 C5 A:DT14 4.9 100.5 1.0 O4 A:DT14 4.9 91.6 1.0 O4 A:PEG112 5.0 95.2 1.0

E.R.Xing, L.A.Yatsunyk. Structure of A Left-Right-Handed G-Quadruplex From the Promoter of the NSD1 Gene To Be Published.