Cobalt in PDB 1eg6: Crystal Structure Analysis of D(Cg(5-Bru)Acg) Complexes to A Phenazine

The structure of Crystal Structure Analysis of D(Cg(5-Bru)Acg) Complexes to A Phenazine, PDB code: 1eg6 was solved by C.J.Cardin, W.A.Denny, J.R.Hobbs, J.H.Thorpe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	15.00 / 2.00
Space group	C 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	29.420, 53.440, 41.320, 90.00, 90.00, 90.00
R / Rfree (%)	22.8 / 34.7

The structure of Crystal Structure Analysis of D(Cg(5-Bru)Acg) Complexes to A Phenazine also contains other interesting chemical elements:

Bromine

(Br)

4 atoms

The binding sites of Cobalt atom in the Crystal Structure Analysis of D(Cg(5-Bru)Acg) Complexes to A Phenazine (pdb code 1eg6). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Crystal Structure Analysis of D(Cg(5-Bru)Acg) Complexes to A Phenazine, PDB code: 1eg6:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Crystal Structure Analysis of D(Cg(5-Bru)Acg) Complexes to A Phenazine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure Analysis of D(Cg(5-Bru)Acg) Complexes to A Phenazine within 5.0Å range: probe atom residue distance (Å) B Occ A:Co40 b:25.5 occ:0.50 O A:HOH42 2.1 40.3 1.0 N7 A:DG6 2.1 20.9 1.0 O A:HOH43 2.1 34.2 1.0 C8 A:DG6 2.9 22.9 1.0 C5 A:DG6 3.3 28.0 1.0 O A:HOH56 3.7 35.4 0.5 O6 A:DG6 3.9 39.4 1.0 C6 A:DG6 4.0 23.3 1.0 O A:HOH46 4.0 43.0 1.0 OP2 A:DG6 4.0 25.3 1.0 N9 A:DG6 4.1 26.1 1.0 C4 A:DG6 4.4 30.5 1.0 O5' A:DG6 5.0 26.2 1.0 P A:DG6 5.0 25.9 1.0

Cobalt binding site 2 out of 2 in the Crystal Structure Analysis of D(Cg(5-Bru)Acg) Complexes to A Phenazine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Crystal Structure Analysis of D(Cg(5-Bru)Acg) Complexes to A Phenazine within 5.0Å range: probe atom residue distance (Å) B Occ B:Co43 b:45.2 occ:1.00 N7 B:DG2 2.1 23.9 1.0 O B:HOH53 2.1 39.5 1.0 O B:HOH55 2.1 56.4 1.0 O B:HOH51 2.1 54.8 1.0 O B:HOH54 2.1 34.7 1.0 O B:HOH52 2.1 49.0 1.0 C8 B:DG2 2.9 26.3 1.0 C5 B:DG2 3.2 24.1 1.0 O6 B:DG2 3.7 23.3 1.0 C6 B:DG2 3.9 23.8 1.0 N9 B:DG2 4.1 25.0 1.0 C4 B:DG2 4.3 26.0 1.0 O B:HOH63 4.4 30.8 1.0 O4 B:DU3 4.5 29.6 1.0 BR B:BR44 4.6 39.5 1.0 OP1 B:DG2 4.7 46.0 0.5 OP2 B:DG2 4.8 41.6 0.5

J.H.Thorpe, J.R.Hobbs, A.K.Todd, W.A.Denny, P.Charlton, C.J.Cardin. Guanine Specific Binding at A Dna Junction Formed By D[Cg(5-Bru)Acg](2) with A Topoisomerase Poison in the Presence of Co(2+) Ions. Biochemistry V. 39 15055 2000.
ISSN: ISSN 0006-2960
PubMed: 11106483
DOI: 10.1021/BI001749P