Cobalt in PDB 1hgw: CEL6A D175A Mutant

All present enzymatic activity of CEL6A D175A Mutant:
3.2.1.91;

The structure of CEL6A D175A Mutant, PDB code: 1hgw was solved by J.-Y.Zou, T.A.Jones, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.97 / 2.1
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	48.630, 74.720, 91.440, 90.00, 103.64, 90.00
R / Rfree (%)	18.3 / 22.5

The binding sites of Cobalt atom in the CEL6A D175A Mutant (pdb code 1hgw). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the CEL6A D175A Mutant, PDB code: 1hgw:

Cobalt binding site 1 out of 1 in the CEL6A D175A Mutant


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of CEL6A D175A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Co999 b:42.3 occ:1.00 OE2 A:GLU146 2.0 21.1 1.0 O A:HOH2243 2.3 19.8 1.0 OE1 A:GLU146 2.4 18.9 1.0 CD A:GLU146 2.5 19.7 1.0 OE1 A:GLU208 3.5 34.3 1.0 CG A:GLU146 4.0 19.1 1.0 CD A:GLU208 4.4 30.6 1.0 O A:HOH2025 4.5 18.0 1.0 OE2 A:GLU208 4.6 35.2 1.0 CB A:GLU146 5.0 14.8 1.0

A.Koivula, L.Ruohonen, G.Wohlfahrt, T.Reinikainen, T.T.Teeri, K.Piens, M.Claeyssens, M.Weber, A.Vasella, D.Becker, M.L.Sinnott, J.-Y.Zou, G.J.Kleywegt, M.Szardenings, J.Stahlberg, T.A.Jones. The Active Site of Cellobiohydrolase CEL6A From Trichoderma Reesei: the Roles of Aspartic Acids D221 and D175 J.Am.Chem.Soc. V. 124 10015 2002.
ISSN: ISSN 0002-7863
PubMed: 12188666
DOI: 10.1021/JA012659Q